Dwarfism – Saarloos Wolfdog

Nanismus

Code: DWARF

Pituitary dwarfism (also called nanism) is a disease that leads to a dwarf growth of dogs and is caused by degeneration of the pituitary gland with a consequent lack of production of growth hormones.

Dwarfism is an autosomal recessive disease, so the disease affects individuals who receive a mutated gene from both parents.

The disease is caused by a deletion of the 7 bp repeat in intron 5 of the LHX3 gene, in one German Shepherd the insertion of the trinucleotide sequence ACA in exon 5 of the same gene was observed.

GenoCan detects both mutations leading to a dwarfism.

Gene and tested mutations/variants

LHX3, c.622-37-31del, c.545_547dupACA

Často kladené dotazy

Saarloos Wolfdog

Mr. Saarloos started breeding these wolfdogs in the first half of the 20th century by mating a German Shepherd with a female wolf from the zoo in Rotterdam, the Netherlands. The Saarloos Wolfdog is a sociable dog and can be a great partner. He is devoted to his owner and shows his love by close contact with humans. On the other hand, the Saarloos is more of an introvert and his stubbornness must be taken into account. He needs a lot of repetition when learning, but you can definitely teach him the basic commands through positive motivation.