It is a neuromuscular disease causing a gradual muscle weakness on the hindlimb and back, which is manifested by poor coordination of movements, cramped and asymmetric walking, or incontinence.
The disease affects a wide range of dog breeds (described in more than 100 breeds) and start to develope at middle or upper age. Unfortunately, the disease is untreatable, it is gradually deteriorating, and after 3-5 years from the first manifestation of the disease, a death frequently occurs due to general weakness and paralysis of the respiratory muscles.
The test might be performed in a partner laboratory.
Gene and tested mutations/variants
SOD1, exon 2
Často kladené dotazy
Lionhound
The Lionhound is a young breed with roots in the Rhodesian Ridgeback. Where the Ridgeback requires the signature dorsal ridge—and excludes ridgeless dogs from breeding—the Lionhound shifts the emphasis to the whole dog rather than a crest of hair. In this breed, the ridge-causing mutation is neither valued nor maintained; over time it is to be bred out of the population. Lionhounds are intelligent, active, and strong-minded—dogs with real charisma. They are friendly and loyal to their families without being pushy. Elegant and agile, they make sporty companions who relish both physical activity and a close, cooperative bond with their people.
